Abstract This essay asks whether the Home global burden of diseases, injuries, and risk factors (GBD) should be measured in terms of their consequences for health, as maintained by most of those who are attempting to measure the GBD, or in terms of their consequences for well-being, as argued by John Broome.It answers that the burden of disease sho
Dam safety is an important issue as it directly influences environmental and life losses.Embankment material and embankment core are important factors that contribute to determining the size and hydraulic characteristics of the breach that occurs due to dam failure.The current topic is to present the analysis of the impact of the dam materials prop
The tumor microenvironment (TME) is an important mediator of breast cancer progression.Cancer-associated fibroblasts constitute a major component of the TME and may originate from tissue-associated fibroblasts or infiltrating mesenchymal stromal cells (MSCs).The mechanisms by which cancer cells activate fibroblasts and recruit MSCs to the TME are l
Since their advent, videolaryngoscopes have played an important role in various types of airway management.Lung isolation techniques are often required for thoracic surgery to achieve one-lung ventilation with a double-lumen tube (DLT) or bronchial blocker (BB).In the case of difficult airways, one-lung ventilation is extremely challenging.The purp
Abstract Genomic imprinting controls parental allele-specific gene expression Socks via epigenetic mechanisms.Abnormal imprinting at the GNAS gene causes multiple phenotypes, including pseudohypoparathyroidism type-1B (PHP1B), a disorder of multihormone resistance.Microdeletions affecting the neighboring STX16 gene ablate an imprinting control regi